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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLAT All Species: 11.21
Human Site: T205 Identified Species: 15.42
UniProt: P10515 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10515 NP_001922.2 647 68997 T205 A A T A S P P T P S A Q A P G
Chimpanzee Pan troglodytes XP_522180 647 68973 T205 A A N A S P P T P S A Q A P G
Rhesus Macaque Macaca mulatta XP_001107013 647 68918 I205 A A T A S P P I P S A Q A P G
Dog Lupus familis XP_546524 647 68802 T205 V A P T L P P T P P A Q A P G
Cat Felis silvestris
Mouse Mus musculus Q8BMF4 642 67923 A204 A P A A A P A A P S A S A P G
Rat Rattus norvegicus P08461 632 67147 A195 A P A A A P A A P S A S A P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509202 536 56600 Q111 Y P P H L Q V Q L P A L S P T
Chicken Gallus gallus XP_417933 681 72018 P234 A A P S P P P P P S P Q A P G
Frog Xenopus laevis NP_001082239 628 66845 Q182 A T P S P P P Q S A V Q A P G
Zebra Danio Brachydanio rerio NP_997832 652 69250 P205 P A T P T S A P A A P Q V P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609118 512 54233 S89 R V P L P A L S P T M E R G S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19749 507 53448 A84 H N R V A L P A L S P T M E L
Sea Urchin Strong. purpuratus XP_001190217 487 52117 V64 A L S P T M E V G T V V R W E
Poplar Tree Populus trichocarpa XP_002303212 512 55370 T89 G M P S L S P T M T E A C L G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q5M729 539 58449 M116 P P H Q E I G M P S L S P T M
Baker's Yeast Sacchar. cerevisiae P12695 482 51800 G59 A A W T K K E G D Q L S P G E
Red Bread Mold Neurospora crassa P20285 458 48601 T35 Y A S Y P P H T V V K M P A L
Conservation
Percent
Protein Identity: 100 99.2 98.1 89.4 N.A. 85.6 85.1 N.A. 70.3 72 72.8 71.9 N.A. 42 N.A. 41.7 39.8
Protein Similarity: 100 99.2 98.6 92.8 N.A. 90.2 89.6 N.A. 74.5 78.4 82.6 78.9 N.A. 53.9 N.A. 55 54.1
P-Site Identity: 100 93.3 93.3 66.6 N.A. 60 60 N.A. 13.3 66.6 46.6 33.3 N.A. 6.6 N.A. 13.3 6.6
P-Site Similarity: 100 93.3 93.3 66.6 N.A. 66.6 66.6 N.A. 20 73.3 60 46.6 N.A. 26.6 N.A. 20 26.6
Percent
Protein Identity: 36.3 N.A. N.A. 38.6 33.5 36.6
Protein Similarity: 50.2 N.A. N.A. 53 48.2 48.8
P-Site Identity: 20 N.A. N.A. 13.3 13.3 20
P-Site Similarity: 33.3 N.A. N.A. 13.3 13.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 53 48 12 30 18 6 18 18 6 12 42 6 48 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 6 0 12 0 0 0 6 6 0 6 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 6 0 0 0 0 0 6 6 6 0 0 0 0 12 59 % G
% His: 6 0 6 6 0 0 6 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 6 0 6 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 6 6 0 0 0 0 6 0 0 0 0 % K
% Leu: 0 6 0 6 18 6 6 0 12 0 12 6 0 6 12 % L
% Met: 0 6 0 0 0 6 0 6 6 0 6 6 6 0 6 % M
% Asn: 0 6 6 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 12 24 36 12 24 53 48 12 53 12 18 0 18 59 0 % P
% Gln: 0 0 0 6 0 6 0 12 0 6 0 42 0 0 0 % Q
% Arg: 6 0 6 0 0 0 0 0 0 0 0 0 12 0 0 % R
% Ser: 0 0 12 18 18 12 0 6 6 48 0 24 6 0 6 % S
% Thr: 0 6 18 12 12 0 0 30 0 18 0 6 0 6 6 % T
% Val: 6 6 0 6 0 0 6 6 6 6 12 6 6 0 0 % V
% Trp: 0 0 6 0 0 0 0 0 0 0 0 0 0 6 0 % W
% Tyr: 12 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _